About Nexalis

About Nexalis Therapeutics

Nexalis Therapeutics is a clinical-stage biopharmaceutical company advancing next-generation therapies for pain and mental health, targeting large, underserved markets with significant unmet need.

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Three differentiated clinical drug candidates advancing through development

Focused on two high-value therapeutic areas with strong commercial demand

Proprietary oral and inhaled delivery platforms designed to improve efficacy and patient outcomes

Total funding facility of $52.3M, providing runway to key clinical milestones

Active clinical programs progressing toward value-inflection points

Seasoned leadership team with a track record of execution in drug development

Our Focus

Therapeutic Areas

We are developing innovative therapies across two critical therapeutic areas - pain management and mental health - using both oral and inhaled drug delivery modalities.

Our pipeline targets conditions with significant unmet medical needs, including treatment-resistant depression, breakthrough cancer pain, and panic disorder.

By leveraging the FDA 505(b)(2) regulatory pathway, we can accelerate development timelines while building on established safety profiles.

3
Drug Candidates
52.3
Funding ($M)
2
Therapeutic Areas
IRX-211
Breakthrough Cancer Pain (BTcP)
Phase 2 Ready
IRX-616a
Panic Disorder
Phase 1 Ready
SRX-25
Treatment-Resistant Depression (TRD)
Phase 1 Planning

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